Mescaline is a naturally occurring psychedelic alkaloid found in certain cacti, primarily in the Lophophora genus. It has been used for centuries by indigenous cultures in Mexico and the southwestern United States for religious and spiritual purposes.
Mescaline is a Schedule I drug in the United States, meaning that it is illegal to possess, use, or distribute. However, it is legal to buy and sell mescaline-containing cacti, such as peyote and San Pedro cactus online or at some specialist plant nurseries.